Michel Ovize Selected Research

triphenyltetrazolium

12/2015	Delayed low pressure at reperfusion: A new approach for cardioprotection.
7/2013	Endoplasmic reticulum stress contributes to heart protection induced by cyclophilin D inhibition.
9/2009	Second-generation sulfonylureas preserve inhibition of mitochondrial permeability transition by the mitochondrial K+(ATP) opener nicorandil in experimental myocardial infarction.
5/2008	Inhibition of GSK3beta by postconditioning is required to prevent opening of the mitochondrial permeability transition pore during reperfusion.
1/2008	Increased mitochondrial calcium coexists with decreased reperfusion injury in postconditioned (but not preconditioned) hearts.
9/2007	Inhibition of mitochondrial permeability transition improves functional recovery and reduces mortality following acute myocardial infarction in mice.
7/2007	Acute myocardial infarction in mice: assessment of transmurality by strain rate imaging.
6/2007	Post-conditioning protects from cardioplegia and cold ischemia via inhibition of mitochondrial permeability transition pore.
12/2005	Trimetazidine inhibits mitochondrial permeability transition pore opening and prevents lethal ischemia-reperfusion injury.
1/2005	Postconditioning inhibits mitochondrial permeability transition.

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Michel Ovize Research Topics

Disease

52	Infarction (Infarctions) 07/2022 - 11/2002
38	Reperfusion Injury 11/2022 - 01/2005
38	ST Elevation Myocardial Infarction 07/2022 - 02/2008
36	Ischemia 01/2021 - 11/2002
32	Myocardial Infarction 05/2022 - 02/2005
14	Ischemic Stroke 05/2022 - 01/2006
13	Stroke (Strokes) 05/2022 - 07/2011
11	Heart Failure 05/2022 - 07/2008
9	Hypoxia (Hypoxemia) 01/2021 - 03/2013
6	Myocardial Ischemia (Ischemic Heart Diseases) 05/2017 - 07/2005
5	Heart Arrest (Cardiac Arrest) 11/2022 - 01/2017
5	Necrosis 12/2020 - 07/2007
4	Inflammation (Inflammations) 01/2021 - 01/2018
3	Hypothermia 11/2022 - 01/2017
3	Thrombosis (Thrombus) 03/2022 - 10/2018
3	Post-Cardiac Arrest Syndrome 01/2022 - 01/2016
3	COVID-19 07/2021 - 01/2020
3	Insulin Resistance 11/2020 - 10/2014
3	Left Ventricular Dysfunction 10/2018 - 10/2003
3	Myocardial Reperfusion Injury 01/2017 - 07/2009
3	Ventricular Remodeling 09/2015 - 03/2010
2	Hypertension (High Blood Pressure) 03/2022 - 01/2021
2	Brain Injuries (Brain Injury) 01/2022 - 01/2019
2	Coronary Artery Disease (Coronary Atherosclerosis) 11/2021 - 10/2003
2	Hemorrhage 01/2021 - 10/2018
2	Hypertrophy 11/2020 - 03/2011
2	Respiratory Insufficiency (Respiratory Failure) 01/2020 - 01/2020
2	Out-of-Hospital Cardiac Arrest 01/2019 - 01/2016
2	Chest Pain (Chest Pains) 10/2018 - 02/2008
2	Atrial Fibrillation 10/2018 - 12/2017
2	Mitochondrial Diseases (Mitochondrial Disease) 03/2016 - 10/2014
2	Multiple Organ Failure (MODS) 01/2016 - 10/2014
2	Wounds and Injuries (Trauma) 01/2016 - 01/2011
2	Body Weight (Weight, Body) 09/2015 - 07/2008
2	Brain Death (Brain Dead) 07/2005 - 11/2002
2	Myocardial Stunning (Stunned Myocardium) 10/2003 - 02/2003
1	Tachycardia (Tachyarrhythmias) 05/2021
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 04/2021
1	Critical Illness (Critically Ill) 04/2021
1	Embolic Stroke 01/2021

Drug/Important Bio-Agent (IBA)

36	Cyclosporine (Ciclosporin)FDA LinkGeneric 11/2022 - 02/2005
28	Mitochondrial Permeability Transition PoreIBA 11/2020 - 01/2005
12	triphenyltetrazoliumIBA 12/2015 - 01/2004
11	Proteins (Proteins, Gene)FDA Link 11/2022 - 09/2007
11	Creatine Kinase (Creatine Phosphokinase)IBA 07/2022 - 10/2005
10	salicylhydroxamic acid (SHAM)IBA 11/2022 - 01/2004
10	Biomarkers (Surrogate Marker)IBA 11/2021 - 02/2008
10	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 10/2019 - 12/2005
6	Cyclophilins (Cyclophilin)IBA 11/2022 - 07/2013
6	(melle-4)cyclosporinIBA 01/2017 - 01/2005
5	Troponin IIBA 12/2020 - 06/2007
4	Interleukin-6 (Interleukin 6)IBA 03/2022 - 01/2019
4	CalciumIBA 01/2018 - 01/2008
4	Coloring Agents (Dyes)IBA 07/2013 - 01/2004
4	EnzymesIBA 01/2013 - 02/2008
3	Biological ProductsIBA 03/2022 - 01/2021
3	Matrix Metalloproteinase 9 (Gelatinase B)IBA 01/2021 - 01/2020
3	Isoflurane FDA LinkGeneric 12/2015 - 11/2002
2	TroponinIBA 11/2022 - 01/2011
2	omega-Chloroacetophenone (Mace)IBA 05/2022 - 11/2020
2	Saline SolutionIBA 01/2022 - 07/2008
2	Morphine (MS Contin)FDA LinkGeneric 05/2021 - 10/2018
2	GadoliniumIBA 01/2021 - 06/2012
2	Sucrose (Saccharose)IBA 01/2021 - 11/2020
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2021 - 01/2018
2	Metformin (Glucophage)FDA LinkGeneric 01/2021 - 10/2014
2	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 12/2020 - 07/2012
2	LipidsIBA 11/2020 - 03/2016
2	Adenosine Triphosphate (ATP)IBA 11/2020 - 09/2009
2	Neuroprotective AgentsIBA 10/2020 - 01/2019
2	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 10/2003
2	Serine (L-Serine)FDA Link 10/2019 - 01/2019
2	Oxygen (Dioxygen)IBA 10/2019 - 02/2003
2	Insulin (Novolin)FDA Link 09/2019 - 10/2014
2	Interleukin-17 (Interleukin 17)IBA 01/2018 - 01/2017
2	Nicorandil (SG 75)IBA 10/2017 - 09/2009
2	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 12/2015 - 06/2007
2	Erythropoietin FDA Link 03/2013 - 05/2012
2	AntioxidantsIBA 01/2013 - 02/2003
2	Dipyridamole (Persantine)FDA LinkGeneric 01/2011 - 10/2003
2	Lactic Acid (Lactate)FDA LinkGeneric 01/2011 - 07/2005
2	CreatinineIBA 01/2011 - 11/2009
1	Peptidyl-Prolyl Isomerase FIBA 11/2022
1	Sodium Lactate FDA LinkGeneric 01/2022
1	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 04/2021
1	Colchicine FDA LinkGeneric 01/2021
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 01/2021

Therapy/Procedure

28	Percutaneous Coronary Intervention 07/2022 - 02/2008
22	Therapeutics 05/2022 - 06/2010
12	Thrombectomy 05/2022 - 07/2012
12	Ischemic Postconditioning 04/2015 - 09/2007
4	Patient Readmission 10/2017 - 06/2015
3	Induced Hypothermia 11/2022 - 01/2017
3	Resuscitation 11/2022 - 01/2011
3	Induced Heart Arrest (Cardioplegia) 01/2020 - 06/2007
2	Injections 11/2020 - 01/2017
2	Patient Care 06/2020 - 10/2019
1	Electric Countershock (Cardioversion) 05/2021
1	Off-Label Use 04/2021
1	Critical Care (Surgical Intensive Care) 04/2021